The psychological and emotional toll of business travel is more abstract, but just as real. Frequent flyers experience “travel disorientation” from changing places and time zones so often. They also suffer mounting stress, given that “time spent travelling will rarely be offset through a reduced workload, and that there may be anxieties associated with work continuing to accumulate (eg ‘inbox overload’) whilst away”.
Oh, you better believe it.
Source: Frequent flyers: The sad, sick life of the business traveller | The Economist